Device and Method for Detection and Treatment of Ventilator Associated Pneumonia in a Mammalian Subject

A method comprising:

• detecting with a contact sensor insertion of an endotracheal tube into a trachea of a mammalian subject, the endotracheal tube including an actively-controllable anchoring cuff including two or more inflatable balloons in contact with an exterior surface of the endotracheal tube;
• detecting pressure of one or more of the inflatable balloons with a pressure sensor;
• and
• actively varying pressure of the one or more of the inflatable balloons of the anchoring cuff under instructions from a controller in communication with the pressure sensor.

A device comprising:

• an endotracheal tube having an interior surface and an exterior surface;
• an actively-controllable anchoring cuff including two or more actively- and independently-controllable inflatable balloons configured to be inflated to differentially varying pressures, wherein the two or more inflatable balloons are configured to contact the exterior surface of the endotracheal tube and configured to contact the trachea of a mammalian subject;
• and
• a controller in communication with the pressure sensor, the controller configured to actively vary pressure within one or more of the two or more inflatable balloons of the anchoring cuff.