Method and Apparatus for Scanning Detection
AssigneeBoard of Regents, The University of Texas System
InventorsPurnendu K. Dasgupta, Brian N. Stamos
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Abstract
An apparatus for scanning and detecting analytes in real time as they move through a separation conduit is provided. The apparatus may include a detector mounted on a scanner containing a separation conduit positions under the scanner such that the scanner may move back and forth along the conduit, producing time and space data of the column as the analyte moves through and providing information regarding elution of the analyte in real time. A method for real time analysis of analytes as they move through a separation conduit is also provided.
Claims29
An apparatus for real time detection of elution of one or more analytes comprising:
- a separation conduit;
- an integrated detector including an excitation source and a sensor, both located immediately adjacent to the separation conduit, wherein the integrated detector is configured to move along a length of the separation conduit;
- and
- a driver moving the integrated detector along the length of the separation conduit;
- wherein the integrated detector scans the separation conduit and detects analyte as it moves through the separation conduit.
A method for detecting elution of one or more analytes in real time, the method comprising:
- injecting an analyte sample through a separation conduit, the analyte sample containing an analyte within an eluent or background electrolyte;
- and
- repeatedly scanning the analyte sample as it moves through the conduit by moving an integrated detector along the length of the separation conduit;
- wherein time and space dependent data obtained from successive scans of the analyte sample is stored, and wherein the data is used to represent successive scans of the analyte sample.
An apparatus for real time detection of elution of one or more analytes comprising:
- a separation conduit;
- an admittance detector located immediately adjacent to the separation conduit, wherein one of the separation conduit and the admittance detector are configured to move relative to the other of the separation conduit and the admittance detector;
- a driver configured to move the admittance detector back and forth along the length of the separation conduit;
- wherein the admittance detector scans a length of the separation conduit and detects analyte as it moves through the length of the separation conduit.
Dependencies are inferred from the claim text.