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AssigneesOregon Health & Science University, The Brigham and Women's Hospital, Inc.
InventorsCharles S. Springer, Jr., Wei Huang, Xin Li, William D. Rooney, Jr., Ian J. Tagge, James A. Balschi, Yajie Zhang
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Provided herein is a Magnetic Resonance Imaging (MRI) technique and, optionally, software, collectively referred to as the “shutter-speed” model, to analyze image data of cancer patients. Embodiments provide a minimally invasive, yet precisely accurate, approach to determining whether tumors are malignant or benign by distinguishing the characteristics of contrast reagent activity in benign and malignant tumors. Exemplary embodiments provide MRI measured biomarkers for tumor malignancy determination and monitoring, effectively eliminating or limiting the false positives suffered by existing MRI techniques while also improving tissue phenotyping and therapeutic intervention monitoring and prediction.
A computer-implemented method for determining a level of cellular metabolic activity for a region of interest, the method comprising:
A method of tissue characterization based on water kinetics, the method comprising:
A computer-implemented method for determining a level of cellular metabolic activity for a region of interest, the method comprising:
Dependencies are inferred from the claim text.