US 2015/0087697 A1 · COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUSCLE PAIN

Abstract

The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I; and methods for treating or preventing muscle pain, a neurological disease, allergy, respiratory diseases or inflammatory disorder may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of muscle disorders, muscle pain, spasticity, neuropathic pain, fibromyalgia, Parkinson's disease, allergy, chronic obstructive pulmonary disease, allergic rhinitis, headache, chronic pain, sub-chronic pain and local pain or its associated complications.

Claims24

Dependent claims

A compound of formula I:

or a pharmaceutically acceptable salt, hydrate, polymorph, solvate, prodrug, enantiomer, or stereoisomer thereof;
Wherein
R1, R2 each independently represents D, methyl, ethyl or propyl;
R3 independently represents D, H,
a is independently 2, 3 or 7;
each b is independently 3, 5 or 6;
e is independently 1, 2 or 6;
c and d are each independently H, D, —OH, —OD, C1-C6-alkyl, —NH2 or —COCH3;
R4 independently represents
a is independently 2, 3 or 7;
each h is independently 3, 5 or 6;
e is independently 1, 2 or 6;
c and d are each independently H, D, —OH, —OD, C1-C6-alkyl, —NH2 or —COCH3;
R5 represents hydrogen, methyl, acetyl or ethyl.

11 more elements

Dependencies are inferred from the claim text.

Compositions and methods for the treatment of muscle pain

Life of this patent

Compositions and methods for the treatment of muscle pain

Life of this patent

Abstract

Claims24