Prebiotic formulations and methods of use
AssigneeRitter Pharmaceuticals, Inc.
InventorsAndrew J. Ritter, Dennis Savaiano, David Barnes, Todd Klaenhammer
Life of this patent
Estimating the term…
Abstract
Provided are methods and pharmaceutical compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and pharmaceutical compositions for improving overall gastrointestinal health or for decreasing symptoms of lactose intolerance by administering to subject in need thereof a pharmaceutical composition comprising a prebiotic, optionally in combination with effective amount of a probiotic microbe or microbes.
Claims30
A method of preventing, treating, or reducing or eliminating one or more symptoms of a gastrointestinal disorder, the method comprising administering to the subject a pharmaceutical composition comprising:
- a. an effective amount of a galactooligosaccharides (GOS) composition to prevent, treat, or reduce or eliminate the one or more symptoms of the gastrointestinal disorder;
- and
- b. one or more excipients,
- wherein the gastrointestinal disorder is constipation, diarrhea, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), small intestine bacterial overgrowth (SIBO), hemorrhoids, indigestion or non-ulcer dyspepsia, anal fissures, perianal abscesses, anal fistula, diverticulosis or diverticulitis, colitis, infectious colitis, ulcerative colitis, Crohn's disease, ischemic colitis, radiation colitis, pseudomembranous colitis, C. difficile colitis, ameboma, anismus, peptic ulcers, colic, biliary colic, gastroenteritis, acrodermatitis enteropathica, ileus, intussusception, polyps, obesity, Hirschsprung's disease, diabetes, or metabolic syndrome.
6-10. (canceled)
13-18. (canceled)
The method of claim 0, wherein the pharmaceutical composition is in a dosage form that is a powder and wherein the powder is packaged in a sachet.
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27-112. (canceled)
A method of treating lactose intolerance in a subject that has experienced one or more symptoms of lactose intolerance, the method comprising administering to the subject a pharmaceutical composition comprising:
- c. an effective amount of a galactooligosaccharides (GOS) composition treat the lactose intolerance;
- and
- d. one or more excipients,
- wherein the effective amount is based on a body mass measurement of the subject.
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119-153. (canceled)
155-180. (canceled)
A pharmaceutical composition in powder form, the composition comprising:
- a. an effective amount of a galactooligosaccharides (GOS) composition to prevent, treat, or reduce or eliminate the one or more symptoms of lactose intolerance;
- and
- b. one or more excipients,
- wherein the pharmaceutical composition comprises from about 10% to about 75% of the one or more excipients by dry weight.
183-271. (canceled)
Dependencies are inferred from the claim text.