Induced neural stem cells
AssigneeMerck Patent GmbH
InventorsFrank Oliver Stefan Edenhoffer, Philipp Woersdoerfer, Yenal Bernhard Lakes, Marc-Christian THIER, Oliver Bruestle
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Abstract
The present invention relates to a method of deriving an induced neural stem cell (iNCS) by nuclear reprogramming of a somatic cell, wherein the method comprises a step of contacting the somatic cell with Oct4 protein or a functionally equivalent analogue, variant or fragment thereof for a limited time period, as well as an induced neural stem cell obtained by this method.
Claims15
A method of deriving an induced neural stem cell (iNCS) by nuclear reprogramming of a somatic cell, wherein the method comprises a step of contacting the somatic cell with an Oct4 protein or a functionally equivalent analogue, variant or fragment thereof for a limited time period.
Dependencies are inferred from the claim text.