Marker sequences for rheumatoid arthritis and use thereof
AssigneeProtagen AG
InventorsJens Beator, Angelika Lüking, Axel Kowald, Helmut E. Meyer
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Abstract
The present invention relates to new marker sequences for rheumatoid arthritis and the diagnostic use thereof together with a method for screening of potential active substances for rheumatoid arthritis by means of these marker sequences. Furthermore, the invention relates to a diagnostic device containing such marker sequences for rheumatoid arthritis, in particular a protein biochip and the use thereof.
Claims3
Use of marker sequences for the diagnosis of rheumatoid arthritis, wherein at least one marker sequence of a cDNA selected from the group SEQ 1-488 or respectively a protein coding therefor or respectively a partial sequence or fragment thereof is determined on or from a patient to be examined.
A method for the diagnosis or risk stratification of rheumatoid arthritis comprising detecting an interaction between a body fluid or tissue extract of a patient and least one marker sequence of a cDNA selected from the group consisting of SEQ ID NOS:
- 1-488 or a protein coding therefor, wherein detection of an interaction indicates the presence of rheumatoid arthritis in said patient.
An arrangement of marker sequences comprising each of the marker sequences of the group SEQ ID NOS:
- 1-488.
Dependencies are inferred from the claim text.