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US 2015/0087006 A1Published application
Cellular cis-co-culture systems and methods
AssigneeLynx Biosciences, Inc.
InventorsChorom Pak, Edmond Wai Keung Young, Natalie Callander, David James Beebe, Shigeki Miyamoto
Life of this patent
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Abstract
The invention relates to systems and methods for studying patient cancer samples in cis-co-culture. For example, the invention provide systems and methods for testing therapeutic agents in vitro in an environment that simulates an in vivo environment to identify agents that are therapeutically effective for the patient.
Claims20
A method for cellular analysis comprising:
- a. placing target cells from a patient on a solid support;
- b. placing stromal cells from the same patient in fluidic connection with the target cells;
- c. contacting the target cells and/or stromal cells with an agent;
- and
- d. measuring an effect or lack of effect of the agent on the target cells and/or stromal cells.
2 more elements
A system for patient-specific in vitro analysis comprising:
- a. a device;
- b. cultured multiple myeloma cells from a patient on or in a region of the device;
- and
- c. cultured bone marrow stromal cells from the same patient on or in the same or a different a region of the device.
1 more element
Dependencies are inferred from the claim text.