Pharmaceutical compositions for inhalation
AssigneeVectura Limited
InventorsJOHN NICHOLAS STANIFORTH, HAGGIS HARRIS, DAVID ALEXANDER VODDEN MORTON, ROBIN BANNISTER
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Abstract
The invention provides microparticles for use in a pharmaceutical composition for pulmonary administration, each microparticle comprising a particle of an active substance having, on its surface, particles of a hydrophobic material suitable for delaying the dissolution of the active substance. The invention also provides a method for making the microparticles.
Claims17
1-31. (canceled)
Microparticles for use in a pharmaceutical composition for pulmonary administration, comprising particles of an active substance having on their surfaces particles of a hydrophobic material comprising magnesium stearate suitable for promoting the dispersal of the active particles on actuation of an inhaler and suitable for delaying the dissolution of the active substance, wherein the particles of hydrophobic material are applied to the particles of active substance during a high shear process, wherein the microparticles comprise an effective amount of one or more of the substances selected from the group consisting of antimuscarinic, a β2-agonist, a steroid, a peptide and a polypeptide.
Dependencies are inferred from the claim text.