Re-establishment of blood flow in blocked human arteries by transferring nano-encapsulated drug through medical devices, designed for the same and releasing the nano-encapsulated drug in human artery with body ph

A drug-delivering insertable medical device for treating a medical condition associated with a body lumen, the body lumen comprising a plurality of layers, the drug-delivering insertable medical device comprising:

• an outer surface coated with a plurality of nano-carriers having a plurality of average diameters, a nano-carrier of the plurality of nano-carriers comprising a drug surrounded by an encapsulating medium, the encapsulating medium comprising at least one of a biological agent, a blood excipient, and a phospholipid, the nano-carrier having an average diameter suitable for penetrating at least one layer of the plurality of layers and a surface of the nano-carrier being devoid of the drug.