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US 2015/0086584 A1Published application
Multi-specific binding agents
AssigneeUniversity of Miami
InventorsEli Gilboa, Randall Brennerman, Brett Schrand
Life of this patent
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Abstract
Compositions comprising aptamers or other binding ligands provide immune cell regulatory signals and specificity to secreted cell molecules at in vivo foci of immune activity.
Claims18
A composition comprising:
- a multi specific agent having specificities for at least at two molecules, wherein a first domain is specific for a secreted cellular molecule and a second domain is specific for an immune cell modulatory molecule.
Dependencies are inferred from the claim text.