Novel Therapeutic Agents

A compound of Formula (I) or an N-oxide thereof, or a pharmaceutically acceptable salt, solvate, polymorph or tautomer of said compound of formula (I) or N-oxide thereof:

• wherein
• Z is (CRaRb)pN(Ra)(CRaRb)q;
• X1 and X2 are each independently selected from halo and OSO2Rc;
• P is
• Q is heteroaryl, which is optionally substituted with alkyl, alkenyl, alkynyl, cycloalkyl, halo, nitro, oxo, cyano or ORe;
• Ra, Rb, Rd and Re are each independently selected from H, alkyl, alkenyl and alkynyl;
• Rc is selected from alkyl, alkenyl and alkynyl;
• and
• p and q are each independently selected from 0, 1, 2, 3 and 4.