Bruton's Tyrosine Kinase Inhibitors for Hematopoietic Mobilzation
AssigneeAcerta Pharma B.V.
InventorsRaquel Izumi, Francisco Salva, Ahmed Hamdy
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Abstract
Methods to improve hematopoiesis and increase white blood cell counts in subjects and patients using pyrimidine-based inhibitors of Bruton's tyrosine kinase (Btk) are disclosed.
Claims21
A method for mobilizing hematopoietic stem and/or progenitor cells in a subject, comprising administering to said subject a pharmaceutical composition comprising a Bruton's Tyrosine Kinase (Btk) inhibitor comprising a pyrimidine ring in an amount effective to mobilize said progenitor cells into the peripheral blood of said subject.
A method of providing hematopoietic cells to a patient in need thereof comprising introducing cells obtained by a method according to any one of claims 10-12 to said patient.
Dependencies are inferred from the claim text.