Aspiration catheters

A system for facilitating aspiration of thrombi comprising:

• a balloon catheter comprising a balloon configured to temporarily occlude a vessel proximal of a thrombus to be aspirated, the balloon catheter comprising a proximal end, a distal end, and a lumen;
• a distal access microcatheter configured to be advanced within the lumen of the balloon catheter and beyond the distal end of the balloon catheter, the distal access microcatheter comprising a proximal end, a distal end and a lumen;
• a microcatheter configured to be advanced within the lumen of the distal access microcatheter and beyond the lumen of the distal access microcatheter, the microcatheter comprising a proximal end, a distal end and a lumen,
• wherein an inner diameter of the distal access microcatheter decreases from the proximal end to the distal end, thereby causing a change in suction pressure within the distal access microcatheter sufficient to affect blood velocity and facilitate thrombus aspiration,
• wherein at least a portion of the distal access microcatheter comprises a hypotube within the lumen of the distal access microcatheter, thereby preventing collapse of the lumen of the distal access microcatheter during application of negative suction,
• wherein the distal access microcatheter comprises an outer polymer coating radially outward of the hypotube and an inner polymer coating radially inward of the hypotube, and
• wherein the negative suction is configured to be applied through a lumen of the distal access microcatheter for thrombus aspiration.

A system for facilitating aspiration of thrombi comprising:

• a distal access microcatheter comprising a proximal end, a distal end and a lumen,
• wherein the distal end of the distal access microcatheter comprises a balloon configured to provide temporary flow arrest within a blood vessel during an aspiration procedure,
• a microcatheter configured to be advanced within the lumen of the distal access microcatheter and beyond the lumen of the distal access microcatheter, the microcatheter comprising a proximal end, a distal end and a lumen,
• wherein an inner diameter of the microcatheter decreases from the proximal end to the distal end, thereby causing a change in suction pressure within the microcatheter sufficient to affect blood velocity and facilitate thrombus aspiration,
• wherein at least a portion of the microcatheter comprises a hypotube within the lumen of the microcatheter, thereby preventing collapse of the lumen of the microcatheter during application of negative suction,
• wherein the microcatheter comprises an outer polymer coating radially outward of the hypotube and an inner polymer coating radially inward of the hypotube, and
• wherein the negative suction is configured to be applied through a lumen of the microcatheter for thrombus aspiration.