Therapy prediction and optimization for renal failure blood therapy, especially home hemodialysis

A renal failure blood therapy system comprising:

• a renal failure blood therapy machine;
• a test including multiple blood samples taken at multiple times during a test therapy to determine concentration levels for each of a first solute and a second solute at each of the multiple times;
• and
• a device programmed to (i) estimate at least one first patient parameter using the determined concentration levels for the first solute, (ii) estimate at least one second patient parameter using the determined concentration levels for the second solute, (iii) determine acceptable therapy duration/frequency combinations for the first solute using the at least one first patient parameter and a first target parameter, and (iv) determine acceptable therapy duration/frequency combinations for the second solute using the at least one second patient parameter and a second target parameter;
• and
• a display device configured to display acceptable therapy duration/frequency combinations for the first solute that overlap with acceptable therapy duration/frequency combinations for the second solute.

A renal failure blood therapy method comprising:

• determining a patient's concentration level of a first solute at multiple times during a therapy;
• determining the patient's concentration level of a second solute at multiple times during the therapy;
• estimating at least one first patient parameter using the determined concentration levels for the first solute;
• estimating at least one second patient parameter using the determined concentration levels for the second solute;
• determining a first plurality of acceptable treatments using the at least one first patient parameter;
• determining a second plurality of acceptable treatments using the at least one second patient parameter;
• and
• merging the first plurality of acceptable treatments with the second plurality of acceptable treatments to determine a plurality of clinically acceptable treatments for both the first solute and the second solute.