End-tidal gas monitoring apparatus
AssigneeFred Hutchinson Cancer Research Center
InventorsJaron Acker, David Christensen, John C. Falligant, Michael A. Insko, John Klaus, Federick J. Montgomery, Christopher Toombs
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Abstract
A non-invasive monitoring apparatus for end-tidal gas concentrations, and a method of use thereof, is described for the detection of endogenous gas concentrations, including respiratory gases, in exhaled breath.
Claims19
An end-tidal gas monitoring apparatus for monitoring gas in the exhaled breath of a mammal comprising:
- a gas conduit configured for fluid communication with the exhaled breath of a mammal;
- a diverter valve in fluid communication with the gas conduit, wherein the diverter valve controls gas flow to a gas sensor downstream of the diverter valve;
- a CO2 sensor upstream of the diverter valve in communication with a controller which determines CO2 levels in the exhaled breath of a mammal to determine when the diverter valve should direct gas flow to the gas sensor;
- and
- a recirculation loop downstream of the diverter valve to provide a continuous gas flow to the gas sensor.
An end-tidal gas monitoring apparatus for monitoring hydrogen sulfide gas in the exhaled breath of a mammal comprising:
- a gas conduit configured for fluid communication with the exhaled breath of a mammal;
- a diverter valve in fluid communication with the gas conduit, wherein the diverter valve controls exhaled breath flow to a hydrogen sulfide gas sensor downstream of the diverter valve;
- a CO2 sensor upstream of the diverter valve to denote the beginning and end of exhalation cycle in communication with a controller which determines end-tidal gas levels in the exhaled breath of a mammal to determine when the diverter valve should direct end-tidal gas flow to the gas sensor;
- and
- a recirculation loop downstream of the diverter valve to provide a continuous gas flow of end-tidal gas to the hydrogen sulfide gas sensor;
- and
- the hydrogen sulfide gas sensors being located in the recirculation loop.
A method for monitoring a gas in exhaled breath of a mammal comprising:
- collecting exhaled breath from a mammal;
- determining a predetermined level of end tidal CO2 in the exhaled breath;
- directing gas flow to a gas sensor upon detection of the predetermined level of end tidal CO2;
- optionally recirculating the exhaled gas to provide a continuous gas flow to the gas sensor;
- and
- determining a level of the exhaled gas in the exhaled breath.
A method for monitoring a gas in exhaled breath of a mammal comprising:
- administering a therapeutic dose of a sulfide containing compound to the mammal to increase blood levels of sulfide;
- collecting exhaled breath from a mammal;
- determining a level of the exhaled gas in the exhaled breath;
- and
- comparing the level of the exhaled gas in the exhaled breath to a predetermined acceptable range of exhaled gas.
Dependencies are inferred from the claim text.