Compositions and methods for improving lactation
AssigneeUniversity of Cincinnati
InventorsNelson Horseman, Laura Hernandez Baumgard
Life of this patent
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Abstract
The present disclosure relates to the use of pharmaceutical agents to manipulate serotonin in animal mammary glands. Use of the serotonin agents results in increased PTHrP levels, resulting in the release of calcium from the bone, which improves lactation.
Claims25
A method for the prevention and/or treatment of periparturient hypocalcemia (milk fever) in lactating female mammals, the method comprising administering to a lactating female mammal in need of such treatment a therapeutically effective amount of a pharmaceutical agent that increases serotonergic signaling.
A method for maintaining calcium homeostasis in lactating female mammals, the method comprising treating the lactating female mammal with an effective amount of a pharmaceutical agent that increases serotonergic signaling.
A method of use of a serotonin agonist in the manufacture of a medicament to increase ruminant serum calcium concentrations, and to increase ruminant milk quality and/or milk yield.
Dependencies are inferred from the claim text.