Method and apparatus for rapid, high sensitivity analysis of low volume samples of biological materials
OwnerPaul Howard Wagner, Adnanul Haq +1inventors
InventorsPaul Howard Wagner, Adnanul Haq, Richard Jerome Schoeneck
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Abstract
A high throughput biological sample processing system includes a sample carrier with a plurality of wells that progresses through the high throughput biological sample processing system. The system further includes a sample dispensing module, a reagent dispensing module, an accumulation/incubation module, and a detection module. The detection module employs an optical measuring device to encapsulate a biological sample in one of the plurality of wells of the sample carrier and detect energy from the chemistry of the biological sample to determine the amount of an analyte in the biological sample.
Claims21
-62. (canceled)
A high throughput biological sample processing system comprising:
- a sample carrier with a plurality of wells that progresses through the high throughput biological sample processing system;
- a sample dispensing module;
- a first reagent dispensing module;
- a first accumulation/incubation module;
- and
- a detection module;
- wherein the detection module employs an optical measuring device to encapsulate a biological sample in one of the plurality of wells of the sample carrier and detect energy from a chemistry of the biological sample to determine the amount of an analyte in the biological sample.
An apparatus for detecting an analyte in a biological sample in a sample carrier with a plurality of wells, the apparatus comprising:
- an optical measuring device comprising an upper optic assembly with a projecting element and a lower optic assembly for receiving the sample carrier;
- wherein the optical measuring device encapsulates a biological sample in one of the plurality of wells of the sample carrier and detects energy from a chemistry of the biological sample to determine the amount of the analyte in the biological sample.
A method of detecting the amount of an analyte in a biological sample in a sample carrier with a plurality of wells, the method comprising:
- feeding the sample carrier into a detection apparatus comprising an optical measuring device comprising an upper optic assembly with a projecting element and a lower optic assembly for receiving the sample carrier;
- clamping the sample carrier between the lower optic assembly and the upper optic assembly to encapsulate a biological sample in one of the plurality of wells of the sample carrier;
- and
- detecting energy from a chemistry of the biological sample to determine the amount of the analyte in the biological sample.
Dependencies are inferred from the claim text.