Lipase Variants and Polynucleotides Encoding Same
AssigneeNovozymes A/S
InventorsJakob Skjold-Joergensen, Jesper Vind, Allan Svendsen
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Abstract
The present invention relates to isolated lipase variants, comprising a substitution at one or more positions corresponding to positions I86D,E,N,Q, E87C, I90D,E,Q, and N92D,E,Q of the mature polypeptide of SEQ ID NO: 2, wherein the variant has lipase activity. In some embodiments the present invention relates to isolated polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; methods of producing the variants; and compositions comprising the variants. The present invention also relates to methods of obtaining lipase variants; methods of cleaning; and use of lipase variants for cleaning.
Claims30
A lipase variant, comprising a substitution at one or more positions in the lid helix corresponding to positions 186D,E,N,Q, E87C, 190D,E,Q, and N92D,E,Q of the mature polypeptide of SEQ ID NO:
- 2, wherein the variant has lipase activity.
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Dependencies are inferred from the claim text.