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US 2015/0031040 A1Published application
Devices, Apparatus, Kit and Method for Treating a Biological Sample
AssigneeSilicon Biosystems S.P.A.
InventorsAlex Calanca, Gianni Medoro, Nicolò Manaresi, Giuseppe Giorgini
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Abstract
Method for the treatment of a biological sample comprising at least one cell and a liquid component; according to the method, a force is applied to the sample inserted in an inner chamber of a hollow device towards a filter which has pores with diameters from 2 nm to 1 μm, so that at least part of the liquid component passes through the filter and the cell remains in the inner chamber, thus obtaining a concentrated sample; the filter has a surface facing the inner chamber of less than 12.6 mm2.
Claims18
A hollow device for treating a biological sample (A;
- B), in particular for separating at least a particle (C) and at least part of a liquid (D) from each other;
- the hollow device (2) comprises an inner chamber (3), which has a volume up to 2 mL;
- a first end (6);
- a first opening (5), which is arranged in the area of the first end (6), establishes a communication between the outside and the inner chamber (3) and has an area of at least 9 mm2;
- and a second end (7);
- the hollow device (3) is characterised in that it comprises a filter (9), which is arranged in the area of the second end (7), separates the inner chamber (3) from the outside, has pores with diameters ranging from 2 nm to 1 μm, an area (S) facing the inner chamber (3) up to 12.6 mm2, and a thickness up to 500 μm.
3 more elements
Dependencies are inferred from the claim text.