Micro-reactor device
AssigneesCapitalBio Corporation, Tsinghua University
InventorsHang LI, Jinglin ZHOU, Dong WANG
Life of this patent
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Abstract
In some aspects, the present disclosure provides a magnetic rack comprising a lateral movement structure and/or a longitudinal movement structure. In particular embodiments, the lateral movement structure and/or longitudinal movement structure move one or more magnets to or away from a reaction tube, in order to control the magnetic forces exerted on microbeads in the reaction tube. The microbeads are attracted onto the reaction tube wall, thereby facilitating separation of the microbeads from a solution in the tube. In particular embodiments, the magnetic rack is used to extract or purify nucleic acid from a sample.
Claims25
A magnetic rack comprising a longitudinal movement structure, the longitudinal movement structure comprising:
- a motor mounting plate;
- a lifting motor;
- a motion platform;
- a magnet holder on the motion platform, which magnet holder is configured to hold one or more magnets,
- wherein the lifting motor is configured to move the motion platform in a direction substantially perpendicular to the motor mounting plate and/or the motion platform.
A magnetic rack comprising a lateral movement structure, the lateral movement structure comprising:
- a motion platform;
- a driving wheel and a driven wheel on the motion platform;
- a timing belt engaging both the driving wheel and the driven wheel;
- and
- a magnet holder engaging the timing belt, which magnet holder is configured to hold one or more magnets,
- wherein the timing belt is configured to be actuated by the driving wheel and to move the magnet holder laterally along a path on the motion platform.
A magnetic rack comprising a lateral movement structure and a longitudinal movement structure, wherein:
- (1) the lateral movement structure comprises:
- a motion platform;
- a driving wheel and a driven wheel on the motion platform;
- a timing belt engaging both the driving wheel and the driven wheel;
- and
- a magnet holder engaging the timing belt, which magnet holder is configured to hold one or more magnets,
- wherein the timing belt is configured to be actuated by the driving wheel and to move the magnet holder laterally along a path on the motion platform;
- and
- (2) the longitudinal movement structure comprises a lifting motor, wherein the lifting motor is configured to move the motion platform in a direction substantially perpendicular to the motion platform.
Dependencies are inferred from the claim text.