Method for analysing foetal nucleic acids

Abstract

The invention relates to a method for analyzing fetal nucleic acids from the supernatant of the culture medium of fetal cell cultures of an in vitro fertilization, comprising the steps: a) removing from the culture vessel used for cultivating the fertilized egg cell the cell-free supernatant of the in vitro fertilization culture medium, which supernatant contains fetal nucleic acid, b) enriching the fetal nucleic acids contained in the supernatant, and c) carrying out an analysis of the nucleic acids present in the cell-free supernatant. The invention further relates to a method for analyzing fetal nucleic acids from the liquid surrounding the embryo within the zona pellucida, the blastocoel or the blastocyst cavity, comprising the steps: a) removing the fluid containing the cell-free fetal nucleic acid from the liquid surrounding the embryo within the zona pellucida, the blastocoel or the blastocyst cavity of the blastula or blastocyst, b) enriching the nucleic acid contained in the fluid surrounding the embryo within the zona pellucida, or the fetal nucleic acids contained in the blastocoel or the blastocyst cavity, and c) carrying out an analysis of the nucleic acids present in the cell-free supernatant.

Dependencies are inferred from the claim text.