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US 2015/0030624 A1Published application
Campylobacter Immunogenic Compositions and Uses Thereof
AssigneeArizona Board of Regents on Behalf of the University of Arizona
InventorsAlexandra Armstrong, Bibiana Law, Lynn A. Joens
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Abstract
The present invention provides immunogenic compositions against Campylobacter and methods for using the immunogenic composition to generate an immune response against Campylobacter and/or reduce intestinal colonization by Campylobacter.
Claims23
An immunogenic composition, comprising one or more expression vectors comprising:
- (a) at least one polynucleotide encoding a protein selected from the group consisting of proteins comprising an amino acid sequence at least 80 percent identical to SEQ ID NO:2 (Cj0998c protein), SEQ ID NO:4 (Cj0588 protein), and SEQ ID NO:6 (Cj0248 protein), or antigenic portions thereof;
- and
- (b) a promoter operatively linked to the polynucleotide, wherein the promoter region is capable of directing expression of the encoded protein(s).
7-8. (canceled)
An immunogenic composition, comprising one or more expression vectors comprising:
- (a) at least one polynucleotide encoding a protein selected from the group consisting of proteins comprising an amino acid sequence at least 80 percent identical to SEQ ID NO:10-106;
- and
- (b) a promoter operatively linked to the polynucleotide, wherein the promoter region is capable of directing expression of the encoded protein(s).
An immunogenic composition, comprising
- (a) one or more isolated proteins selected from the group consisting of proteins comprising an amino acid sequence at least 80 percent identical to SEQ ID NO:2 (Cj0998c protein), SEQ ID NO:4 (Cj0588 protein), and SEQ ID NO:6 (Cj0248 protein), or antigenic portions thereof;
- and
- (b) a pharmaceutically acceptable carrier.
19-22. (canceled)
26-30. (canceled)
Dependencies are inferred from the claim text.