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US 2015/0030596 A1Published application
BISPECIFIC CHIMERIC PROTEINS WITH DARPins
AssigneeSamsung Electronics Co., Ltd.
InventorsKwang Ho CHEONG, Young Jun Koh, Min-Kyung Kim, Powei Lin, Seung Hyun Lee, Jung Wook Lee, Mi Young Cho, Jae Woong Hwang
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Abstract
A bispecific chimeric protein including a designed ankyrin repeat protein (DARPin), and an IgG antibody, an scFv-Fc antibody fragment, or a combination thereof, linked to the DARPin; a method for treating or preventing cancer using the same; and related methods and compositions.
Claims21
A bispecific chimeric protein comprising:
- a designed ankyrin repeat protein (DARPin), and
- an IgG antibody, an scFv-Fc antibody fragment, or a combination thereof, linked to the DARPin.
A method of preparing a bispecific chimeric protein comprising
- i) linking a DARPin, and
- ii) an IgG antibody or an scFv-Fc antibody fragment, or a combination thereof, to provide a bispecific chimeric protein.
Dependencies are inferred from the claim text.