Lysosomal Storage Disease Enzyme
AssigneeSynageva BioPharma Corp.
InventorsAlex J. Harvey, Anthony Quinn
Life of this patent
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Abstract
The present invention provides compositions of recombinant human lysosomal acid lipase having particular glycosylation patterns for internalization into target cells, a vector containing the nucleic acid encoding human lysosomal acid lipase, a host cell transformed with the vector, pharmaceutical compositions comprising the recombinant human lysosomal acid lipase and method of treating conditions associated with lysosomal acid lipase deficiency.
Claims7
1-43. (canceled)
A composition comprising a mixture of recombinant human lysosomal acid lipase (LAL), the mixture comprising at least two human LAL selected from the group consisting of SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4 and SEQ ID NO:19.
45-68. (canceled)
Dependencies are inferred from the claim text.