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US 2015/0030579 A1Published application
Hydroxytyrosol combinations for enhancing mitochondrial function and energy production
AssigneeDsm IP Assets B.V.
InventorsAnn FOWLER, Angelika FRIEDEL, Darko KNUTTI, Karin KURATLI, Daniel RAEDERSTORFF, Ying WANG-SCHMIDT, Karin WERTZ
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Abstract
Hydroxytyrosol or olive juice containing hydroxytyrosol in combination with at least one of the compounds selected from the group consisting of: creatine, coenzyme Q10, resveratrol, caffeine, carnitine, B vitamins (B1, B2, B3, B5, B6, and/or B12) and ginseng (preferably: root) extract. can be used to maintain or increase mitochondrial biogenesis in cardiac muscle, skeletal muscles, and liver tissue.
Claims5
A method of increasing mitochondia biogenesis in a mammal comprising:
- (a) administering to a mammal in need of increased mitochondia biogenesis an effective amount of a composition comprising hydroxytyrosol in combination with at least one compound selected from the group consisting of creatine, coenzyme Q10, resveratrol, caffeine, carnitine, B vitamins (B1 or thiamine;
- B2 or riboflavin;
- B3 or niacin or niacinamide;
- B5 or pantothenic acid;
- B6 or pyridoxine, pyridoxal, pyridoxamine, or pyridoxine hydrochloride;
- B7 or biotin;
- B9 or folic acid;
- or B12 or various cobalamins, such as cyanocobalamin), quercetin, alpha-lipoic acid, epigallocatechin (EGCG) and ginseng extract;
- and
- (b) observing a mitochondria biogenesis effect.
7 more elements
Dependencies are inferred from the claim text.