Molecular code systems
AssigneeETH Zurich
InventorsRobert N. GRASS, Wendelin Jan STARK
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Abstract
The present invention relates to a method for protecting and. recovering nucleic acids. This method may be applied in a verification method of products using molecular code systems or it may be applied in a storage method for nucleic acids. The invention further provides specific particles, their use in secure marking; products suitable for such verification method, to processes for manufacturing such products and methods for reading the information.
Claims17
A verification method for a product, wherein
- a. said product comprises a matrix and particles,
- b. said particles comprise (i) a nucleic acid core and (ii) a non-porous silica coating, and wherein
- c. said method comprises the step of dissolving said particles in an aqueous fluoride solution,
- and wherein said non-porous silica coating has a porosity below 0.1 cm3/g of pores of the open, intraparticle type and meso size.
(canceled)
A product selected from the group consisting of bulk materials of polymers, paints and dyes, packaging materials, pharmaceuticals and food products;
- said product comprising a matrix and particles, wherein
- a. said matrix contains polymeric material;
- and
- b. said particles contain a nucleic acid core and a non-porous silica coating.
- c. said particles are present in an amount of 1 ppm or less.
A storage method for nucleic acids, comprising the steps of:
- a. providing particles comprising a nucleic acid core and a non-porous silica coating;
- b. storing the thus obtained particles;
- and
- c. dissolving said particles in an aqueous buffered fluoride solution.
A data base of nucleic acids comprising a multitude of core shell particles, wherein
- a. said particles comprise a nucleic acid core and a non-porous silica coating and
- b. said particles are spatially separated according to the nucleic acids comprised in their core.
Dependencies are inferred from the claim text.