Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution

A method for generating data associated with at least one portion of an anatomical sample, comprising:

• forwarding at least one first radiation at to the at least one portion through at least one optical arrangement, and receiving at least one second radiation from the at least one portion which is based on the at least one first radiation;
• forwarding at least one third radiation to the at least one portion through the at least one optical arrangement, and receiving at least one fourth radiation from the at least one portion which is based on the at least one third radiation;
• receiving at least one fifth radiation from a reference arrangement and combining at least one of the second radiation or the fourth radiation with at least one fifth radiation to generate a further radiation;
• and
• generating the data as a function of the further radiation,
• wherein the at least one optical arrangement is configured to be illuminated by a ring-shaped beam which has a plurality of rings that include at least one of respective diameters or respective thicknesses that are different from one another.

An apparatus for generating data associated with at least one portion of an anatomical sample, comprising:

• at least one optical arrangement;
• at least one radiation transceiving arrangement configured to:
• (i) forward at least one first radiation at to the at least one portion through the at least one optical arrangement,
• (ii) receive at least one second radiation from the at least one portion which is based on the at least one first radiation,
• (iii) forward at least one third radiation to the at least one portion through the at least one optical arrangement,
• (iv) receive at least one fourth radiation from the at least one portion, which is based on the at least one third radiation,
• (v) receive at least one fifth radiation from a reference arrangement, and
• (vi) combine at least one of the second radiation or the fourth radiation with at least one fifth radiation to generate a further radiation;
• and
• at least one computer arrangement configured to generate the data as a function of the further radiation,
• wherein the at least one optical arrangement is configured to be illuminated by a ring-shaped beam which has a plurality of rings that include at least one of respective diameters or respective thicknesses that are different from one another.

A method for generating data associated with at least one portion of an anatomical sample, comprising:

• forwarding at least one first radiation at to the at least one portion through at least one optical arrangement, and receiving at least one second radiation from the at least one portion which is based on the at least one first radiation, wherein, based on an interaction between the at least one optical arrangement and at least one of the first radiation or the second radiation, the at least one optical arrangement has a first transfer function;
• forwarding at least one third radiation to the at least one portion through the at least one optical arrangement, and receiving at least one fourth radiation from the at least one portion which is based on the at least one third radiation, wherein, based on an interaction between the at least one optical arrangement and at least one of the third radiation or the fourth radiation, the at least one optical arrangement has a second transfer function, and wherein the first transfer function is at least partially different from the second transfer function;
• and
• generating the data based on the second and fourth radiations, wherein the at least one optical arrangement includes at least one of a ball lens or an elliptical lens.

An apparatus for generating data associated with at least one portion of an anatomical sample, comprising:

• at least one optical arrangement;
• at least one radiation transceiving arrangement configured to:
• (i) forward at least one first radiation at to the at least one portion through the at least one optical arrangement,
• (ii) receive at least one second radiation from the at least one portion which is based on the at least one first radiation, wherein, based on an interaction between the at least one optical arrangement and at least one of the first radiation or the second radiation, the at least one optical arrangement has a first transfer function,
• (iii) forward at least one third radiation to the at least one portion through the at least one optical arrangement, and
• (iv) receive at least one fourth radiation from the at least one portion which is based on the at least one third radiation, wherein, based on an interaction between the at least one optical arrangement and at least one of the third radiation or the fourth radiation, the at least one optical arrangement has a second transfer function, and wherein the first transfer function is at least partially different from the second transfer function;
• and
• at least one computer arrangement configured to generate the data based on the second and fourth radiations, wherein the at least one optical arrangement includes at least one of a ball lens or an elliptical lens.