Droplet actuator and method
AssigneeAdvanced Liquid Logic, Inc.
InventorsMichael G. Pollack, Prasanna Thwar, Vamsee K. Pamula, Vijay Srinivasan, Allen E. Eckhardt, Alexander Shenderov, Dwayne J. Allen
Life of this patent
Estimating the term…
Abstract
The invention provides droplet actuators and droplet actuator cassettes including reagent storage capabilities, as well as methods of making and using the droplet actuators and cassettes. The invention also provides continuous flow channel elements and techniques for using electrodes to manipulate droplets in flowing streams. The invention also discloses methods of separating compounds on a droplet actuator. Various other aspects of the invention are also disclosed.
Claims21
1-173. (canceled)
A droplet actuator comprising:
- (a) two substrates separated by a droplet operations gap;
- (b) one or more electrodes associated with one or both substrates and arranged for conducting one or more droplet operations in the droplet operations gap;
- (c) a reagent storage cassette comprising one or more reservoirs comprising one or more liquids;
- and
- (d) a fluid path from the one or more reservoirs into the droplet operations gap, wherein the fluid path is blocked by a film.
A method comprising:
- (a) providing a channel;
- (b) flowing an immiscible liquid including a droplet through the channel and into proximity with a set of one or more electrodes;
- (c) using the set of one or more electrodes with the droplet to conduct a droplet operation;
- and
- (d) continuing to flow the droplet or one or more daughter droplets formed during the droplet operation through the channel.
Dependencies are inferred from the claim text.