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US 2015/0027445 A1Published application
Systems and methods for intra-pulmonary percussive ventilation integrated in a ventilator
AssigneeKoninklijke Philips N.V.
InventorsSmita Garde, Samir Ahmad
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Abstract
System and methods for providing respiratory therapy include predetermined and/or automatically determined perturbations of levels of pressure, flow, and/or other gas parameters integrated and/or combined (Start with a supplied pressurized flow of breathable gas for a subject. The perturbations are intended to improve secretion management through intra-pulmonary percussive ventilation integrated with ventilation therapy.
Claims15
A respiratory therapy system comprising:
- a pressure generator configured to generate a pressurized flow of breathable gas for delivery to the airway of a subject;
- one or more sensors configured to generate one or more output signals conveying information related to one or more gas parameters of the pressurized flow of breathable gas;
- and
- one or more processors configured to execute computer program modules, the computer program modules comprising:
- a therapy module configured to determine levels of one or more gas parameters of the pressurized flow of breathable gas as a function of time in accordance with a respiratory therapy regime;
- a perturbation module configured (i) to determine one or more perturbation parameters defining perturbations to be applied to the levels of the one or more gas parameters determined by the therapy module and (ii) to output a perturbation parameter control signal, wherein one of the perturbation parameters includes a range of frequencies of perturbations to be applied to the levels of the one or more gas parameters;
- a control module configured to control the pressure generator to adjust the one or more gas parameters of the pressurized flow of breathable gas such that the levels of the one or more gas parameters in the pressurized flow of breathable gas are the levels determined by the therapy module with the perturbations defined by the perturbation module;
- and
- a breathing parameter determination module configured (i) to determine one or more breathing parameters and gas parameters based on (i)(a) the one or more generated output signals and (i)(b) the perturbation parameters determined by the perturbation module and (ii) to output a breathing parameter control signal,
- wherein the control module is further configured to adjust, in response to the breathing parameter control signal and the perturbation parameter control signal, the levels of the one or more gas parameters in the pressurized flow of breathable gas within the determined range of frequencies, and
- wherein the perturbation module further determines perturbation parameters defining perturbations selected from the group consisting of:
- (i) perturbations that gradually, across multiple respiratory cycles, sweep through the range of frequencies, (ii) perturbations having a randomly determined frequency within the range of frequencies for one or more respiratory cycles, and (iii) perturbations having a frequency determined according to one or more predetermined patterns.
9 more elements
(canceled)
A method for providing respiratory therapy, the method comprising:
- generating a pressurized flow of breathable gas for delivery to the airway of a subject;
- generating one or more output signals conveying information related to one or more gas parameters of the pressurized flow of breathable gas;
- determining levels of one or more gas parameters of the pressurized flow of breathable gas as a function of time in accordance with a respiratory therapy regime;
- determining one or more perturbation parameters defining perturbations to be applied to the determined levels of the one or more gas parameters, wherein one of the perturbation parameters includes a range of frequencies of perturbations to be applied to the levels of the one or more gas parameters;
- determining one or more breathing parameters and gas parameters based on (a) the one or more generated output signals and (b) the determined perturbation parameters and outputting a breathing parameter control signal;
- and
- adjusting the one or more gas parameters of the pressurized flow of breathable gas based on the one or more breathing parameters, such that the levels of the one or more gas parameters of the pressurized flow of breathable gas are the determined levels in accordance with the respiratory therapy regime with the perturbations applied to the determined levels, further adjusting, in response to the breathing parameter control signal and the perturbation parameter control signal, the levels of the one or more gas parameters in the pressurized flow of breathable gas within the determined range of frequencies, and
- wherein determining the perturbation parameters further includes defining perturbations selected from the group consisting of:
- (i) perturbations that gradually, across multiple respiratory cycles, sweep through the range of frequencies, (ii) perturbations having a randomly determined frequency within the range of frequencies for one or more respiratory cycles, and (iii) perturbations having a frequency determined according to one or more predetermined patterns.
6 more elements
(canceled)
A system for providing respiratory therapy, the system comprising:
- means for generating a pressurized flow of breathable gas for delivery to the airway of a subject;
- means for generating one or more output signals conveying information related to one or more gas parameters of the pressurized flow of breathable gas;
- means for determining levels of one or more gas parameters of the pressurized flow of breathable gas as a function of time in accordance with a respiratory therapy regime;
- means for determining one or more perturbation parameters defining perturbations to be applied to the determined levels of the one or more gas parameters and for outputing a perturbation parameter control signal, wherein one of the perturbation parameters includes a range of frequencies of perturbations to be applied to the levels of the one or more gas parameters;
- means for determining one or more breathing parameters and gas parameters based on the one or more generated output signals and the determined perturbation parameters and outputting a breathing parameter control signal;
- and
- means for adjusting the one or more gas parameters of the pressurized flow of breathable gas based on the one or more breathing parameters, such that the levels of the one or more gas parameters of the pressurized flow of breathable gas are the determined levels in accordance with the respiratory therapy regime with the perturbations applied to the determined levels,
- wherein the adjusting means is further configured to adjust, in response to the breathing parameter control signal and the perturbation parameter control signal, the levels of the one or more gas parameters in the pressurized flow of breathable gas within the determined range of frequencies, and
- wherein the perturbation determining means further determines perturbation parameters defining perturbations selected from the group consisting of:
- (i) perturbations that gradually, across multiple respiratory cycles, sweep through the range of frequencies, (ii) perturbations having a randomly determined frequency within the range of frequencies for one or more respiratory cycles, and (iii) perturbations having a frequency determined according to one or more predetermined patterns.
7 more elements
(canceled)
Dependencies are inferred from the claim text.