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US 2015/0021265 A1Published application
Flow splitting in supercritical fluid chromatography systems
AssigneeWaters Technologies Corporation
InventorsMichael R. Jackson, James E. Usowicz, Lucas O. Tiziani, Joseph A. Jarrell, Douglas P. Wittmer
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Abstract
A method includes passing a mobile phase fluid flow comprising liquefied CO2 through a separation column; then introducing a makeup fluid flow into the mobile phase fluid flow to form a mixed fluid flow; and then splitting the mixed fluid flow.
Claims22
A method comprising:
- passing a mobile phase fluid flow comprising liquefied CO2 through a separation column;
- then
- introducing a makeup fluid flow into the mobile phase fluid flow to form a mixed fluid flow;
- and then
- splitting the mixed fluid flow.
2 more elements
(canceled)
A supercritical fluid chromatography (SFC) system comprising:
- a separation column;
- a flow splitter in fluidic communication with the separation column;
- a makeup pump for introducing a makeup fluid flow into the system;
- and
- a mixing tee arranged in a position downstream of the separation column and upstream of the flow splitter, the mixing tee being configured to mix the makeup fluid flow with a mobile phase fluid flow from the separation column to form a mixed fluid flow, wherein the flow splitter is configured to split the mixed fluid flow.
2 more elements
(canceled)
Dependencies are inferred from the claim text.