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US 2015/0010647 A1Published application
Methods for Identifying Fragile Histidine Triad (FHIT) Interaction and Uses Thereof
AssigneeThe Ohio State University
InventorsCarlo M. Croce, Francesco Trapasso
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Abstract
Provided herein are methods and compositions for the diagnosis, prognosis and treatment of a cancer associated disorders using the Fhit gene.
Claims19
A method of sensitizing at least one cell to a chemotherapeutic agent comprising:
- exposing the at least one cell to an exogenous fragile histidine triad (Fhit) gene product in an amount sufficient to sensitize the at least one cell;
- and thereafter,
- administering a chemotherapeutic agent to the at least one sensitized cell.
A pharmaceutical composition for treating a cancer associated disorder, comprising at least one isolated Fhit gene product, and a pharmaceutically-acceptable carrier.
Dependencies are inferred from the claim text.