Adaptive System for Optimizing a Drug Dosage Regimen Over Time

A system for optimizing a patient's basal insulin dosage regimen over time, comprising:

• a blood glucose meter for receiving a patient blood sample and generating a blood glucose data set corresponding to a blood glucose value of the patient blood sample,
• memory means adapted to receive:
• data representing an initial basal insulin dosage regimen, and
• blood glucose data sets corresponding to a plurality of blood glucose values as a function of time,
• a processor operatively connected to the memory means, the processor being programmed to determine from blood glucose data sets determined at a plurality of times whether and by how much to vary a component in the patient's present insulin dosage regimen in order to maintain the patient's future blood-glucose-level measurements within a predefined range, and
• output means for communicating to the patient the determined variation in the component in the patient's insulin dosage regimen,
• wherein the processor is programmed to calculate:
• a correction value representing, for blood glucose data sets determined at a plurality of times, the degree of deviation between determined and expected values,
• wherein the calculated variation of the component is reduced as a function of the calculated correction value.