Thermal treatment of the skin surface with coated metal nanoparticles
AssigneeSienna Labs, Inc.
InventorsTodd James Harris, Alice Ann Chen Kim
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Abstract
Treatment of skin tissue with photoactive materials and light, such as nanoparticles and formulations which are useful for cosmetic, diagnostic and therapeutic applications to mammals such as humans. In particular, embodiments of thermal treatment of the skin surface with coated metal nanoparticles are disclosed.
Claims1
A method for performing thermoablation, comprising the steps of contacting a target tissue region of a mammalian subject with a composition comprising a plurality of plasmonic nanoparticles under conditions such that an effective amount of the plasmonic nanoparticles localize to a domain of the target tissue region;
- and exposing the target tissue region to energy delivered from a nonlinear excitation surface plasmon resonance source in an amount effective to induce thermoablation of the domain of the target tissue region, wherein the nanoparticle comprises a coat on a surface of the nanoparticle, wherein the coat comprises a polar moiety, non-polar moiety, charged moiety, ionic moiety, basic moiety, acidic moiety, oxidative moiety, hydrophobic moiety, hydrophilic moiety, agonistic moiety, antagonistic moiety, or reactive moiety.
Dependencies are inferred from the claim text.