Ingenane-type diterpene compound, and pharmaceutical composition for treating or preventing viral infectious diseases containing same

A method for preventing or treating viral infectious diseases, comprising administering a pharmaceutical composition to a subject having a viral infectious disease occurrence or a risk thereof with a therapeutically effective dose, wherein the composition comprises a compound represented by Chemical Formula 2 or a pharmaceutically acceptable salt thereof as an active ingredient.

• wherein, in the formula,
• R1 is H, R2 is H, R3 is OCO—(CH2)10—CH3 and R4 is CO—CH(CH3)—CH(CH3)2;
• R1 is CO—CH(CH3)—CH(CH3)2, R2 is H, R3 is OCO—(CH2)10—CH3 and R4 is H;
• R1 is H, R2 is OCO—(CH2)8—CH3, R3 is H and R4 is H;
• R1 is CO(CH═CH)—(CH2)4—CH3, R2 is OAc, R3 is H and R4 is H;
• R1 is CO—CH(CH3)—CH(CH3)2, R2 is OCO—(CH2)14—CH3, R3 is OCO—(CH2)10—CH3 and R4 is H;
• or
• R1 is CO—CH(CH3)—CH(CH3)2, R2 is OH, R3 is OCO—(CH2)10—CH3 and R4 is H.

A method for preventing or ameliorating viral infectious diseases, comprising administering a health functional food to a subject having a viral infectious disease occurrence or a risk thereof, wherein the health functional food comprises a compound represented by Chemical Formula 2 or a sitologically acceptable salt thereof as an active ingredient:

• wherein, in the formula,
• R1 is H, R2 is H, R3 is OCO—(CH2)10—CH3 and R4 is CO—CH(CH3)—CH(CH3)2;
• R1 is CO—CH(CH3)—CH(CH3)2, R2 is H, R3 is OCO—(CH2)10—CH3 and R4 is H;
• R1 is H, R2 is OCO—(CH2)8—CH3, R3 is H and R4 is H;
• R1 is CO(CH═CH)—(CH2)4—CH3, R2 is OAc, R3 is H and R4 is H;
• R1 is CO—CH(CH3)—CH(CH3)2, R2 is OCO—(CH2)14—CH3, R3 is OCO—(CH2)10—CH3 and R4 is H;
• or
• R1 is CO—CH(CH3)—CH(CH3)2, R2 is OH, R3 is OCO—(CH2)10—CH3 and R4 is H.

A method of enhancing production of interferon-gamma in a subject, comprising administering a composition to the subject, wherein the composition comprises a compound represented by Chemical Formula 2 or a pharmaceutically acceptable salt thereof as an active ingredient.

• wherein, in the formula,
• R1 is H, R2 is H, R3 is OCO—(CH2)10—CH3 and R4 is CO—CH(CH3)—CH(CH3)2;
• R1 is CO—CH(CH3)—CH(CH3)2, R2 is H, R3 is OCO—(CH2)10—CH3 and R4 is H;
• R1 is H, R2 is OCO—(CH2)8—CH3, R3 is H and R4 is H;
• R1 is CO(CH═CH)—(CH2)4—CH3, R2 is OAc, R3 is H and R4 is H;
• R1 is CO—CH(CH3)—CH(CH3)2, R2 is OCO—(CH2)14—CH3, R3 is OCO—(CH2)10—CH3 and R4 is H;
• or
• R1 is CO—CH(CH3)—CH(CH3)2, R2 is OH, R3 is OCO—(CH2)10—CH3 and R4 is H.