Mandelic acid condensation polymers
AssigneesThe Board of Trustees of the University of Illinois, Rush University Medical Center
InventorsRobert A. Anderson, JR., Xiao-Hui Diao, Lourens J.D. Zaneveld, Calvin J. Chany, II, Aleksej Krunic, Donald P. Waller, Duane L. Venton, Sanjay Jain
Life of this patent
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Abstract
Disclosed herein are compounds and compositions useful for reducing the risk of infection. In particular, disclosed herein are mandelic acid condensation polymers, compositions comprising such compounds, processes for producing such compounds, and methods of using such compounds.
Claims66
A compound of formula (I)
- or a pharmaceutically acceptable salt, ester, amide, or prodrug form thereof, wherein
- R1, R2, and R3 are each independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycle, heteroaryl, aryl, and counterion;
- R4 is independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycle, heteroaryl, and aryl;
- R5, R6, and R7 are each independently selected from the group consisting of alkyl, alkoxy, hydroxy, and halogen;
- n is an integer greater than zero;
- and
- x, y, and z are each an integer independently selected from the group consisting of 0, 1, 2, 3, and 4.
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A process for producing mandelic acid condensation polymers, comprising:
- cooling a strong acid to a temperature below 0° C.;
- and
- adding mandelic acid or a mandelic acid derivative to the strong acid to provide a reaction mixture.
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Dependencies are inferred from the claim text.