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US 2014/0371253 A1Published application
Cyclopamine Analogs
AssigneeInfinity Pharmaceuticals, Inc.
InventorsBrian Austad, Mark L. Behnke, Alfredo C. Castro, Michael J. Grogan, Somarajannair Janardanannair, Andre Lescarbeau, Stephane Peluso, Andre B. Charette, Martin R. Tremblay
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Abstract
The invention provides novel derivatives of cyclopamine having the following formula:
Claims16
-25. (canceled)
A compound having the structure:
- where R is selected from the group consisting of —H, —OH, and a nitrogen protecting group,
- or a pharmaceutically acceptable salt thereof.
A pharmaceutical composition comprising a compound having the structure:
- where R is selected from the group consisting of —H, —OH, and a nitrogen protecting group, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.