Crystal of a free tricyclic pyrazolopyrimidine derivative
AssigneeDaiichi Sankyo Company, Limited
InventorsYasusi Ueda, Nobuyuki Suzuki, Hitoshi Ohki
Life of this patent
Estimating the term…
Abstract
To provide a crystal of a tricyclic pyrazolopyrimidine compound inhibiting the effect of HSP90. The present invention provides a crystal of 2-{4-amino-2-[(3-chloro-4-methoxy-5-methylpyridin-2-yl)methyl]-2,7-dihydro-6-thia-1,2,3,5-tetraazabenzo[cd]azulen-8-yl}-N-methylacetamide which inhibits the ATPase activity of HSP90 and which has antitumor activity, a medicament comprising the same, an anticancer agent comprising the same, and the like.
Claims3
A crystal of 2-{4-amino-2-[(3-chloro-4-methoxy-5-methylpyridin-2-yl)methyl]-2,7-dihydro-6-thia-1,2,3,5-tetraazabenzo[cd]azulen-8-yl}-N-methylacetamide represented by the following formula (1):
- wherein the crystal has the X-ray diffraction pattern shown in FIG. 2, in an X-ray powder diffraction pattern obtained by irradiation with copper Kα radiation (wavelength λ=1.54 angstroms).
Dependencies are inferred from the claim text.