Antifibrotic compounds and uses thereof

A compound as described in Formula (I) below:

• or a pharmaceutically acceptable salt thereof or a prodrug thereof;
• where in R1 is —COOR5;
• R2 is H or a prodrug moiety, optionally a carbamate or amide;
• R3 and R4 are independently H, aryl or heteroaryl, which may optionally be independently substituted with one or more lower alkyl, halogen, OR6, NO2, CN, NH2, NR6R7, NR6COR7 or NR6SO2R7 moieties;
• R5 is a lower alkyl group;
• R6 and R7 are independently hydrogen or alkyl, cycloalkyl, heterocycle, cycloalkylalkyl, alkylcycloalkylalkyl, heterocycloalkyl or alkylheterocycloalkyl, which may optionally substituted with alkyl, OR8, COOR8, NR8R9, or NCOR8 moieties;
• R8 and R9 are independently H or a lower alkyl group;
• A is N or CH, wherein one A is nitrogen;
• and
• B is O or S.