Atmospheric Pressure Chemical Ionization Detection
AssigneeWaters Technologies Corporation
InventorDouglas M. Stevens
Life of this patent
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Abstract
An atmospheric pressure chemical ionization detector includes a reaction chamber that is configured to receive gas phase analytes. An electrode is disposed within the reaction chamber and is configured to ionize the gas phase analytes via corona discharge. A collector is disposed adjacent an outlet of the reaction chamber and is configured to attract ions from the chamber such that the ions hit the collector to induce a measurable current. The detector is configured for non-mass spectrometric detection of gas phase analyte ions.
Claims21
An atmospheric pressure chemical ionization detector comprising:
- a reaction chamber configured to receive gas phase analytes;
- an electrode disposed within the reaction chamber and configured to ionize the gas phase analytes via corona discharge;
- and
- a collector disposed adjacent an outlet of the reaction chamber and configured to attract ions from the chamber such that the ions hit the collector to induce a measurable current,
- wherein the detector is configured for non-mass spectrometric detection of gas phase analyte ions.
A method comprising:
- passing a flow of a first gas carrying a sample through a gas chromatograph;
- merging a flow of a second gas with effluent from the gas chromatograph to provide a mixed gas flow;
- generating ions by passing the mixed gas flow through a corona discharge;
- and
- measuring a cumulative ion intensity of the generated ions without passing the ions through a mass analyzer.
A method comprising:
- passing a flow of a first gas carrying a sample through a gas chromatograph;
- merging a flow of a second gas with effluent from the gas chromatograph to provide a mixed gas flow;
- generating ions by passing the mixed gas flow through a corona discharge;
- and
- measuring a cumulative ion intensity of the generated ions without separating the ions according to their respective mass-to-charge ratios.
A method comprising:
- passing a flow of a first gas carrying a sample through a gas chromatograph;
- merging a flow of a second gas with effluent from the gas chromatograph to provide a mixed gas flow;
- generating ions by passing the mixed gas flow through a corona discharge;
- and
- performing non-mass spectrometric detection of the generated ions.
Dependencies are inferred from the claim text.