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AssigneeUniversity of Washington
InventorsShaoyi Jiang, Zheng Zhang, Shengfu Chen, Hana Vaisocherova
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Dual-functional nonfouling surfaces and materials, methods for making dual-functional nonfouling surfaces and materials, and devices that include dual-functional nonfouling surfaces and materials. The dual-functional surfaces are nonfouling surfaces that resist non-specific protein adsorption and cell adhesion. The dual-functional surfaces and materials include covalently coupled biomolecules (e.g., target binding partners) that impart specific biological activity thereto. The surfaces and materials are useful in medical diagnostics, biomaterials and bioprocessing, tissue engineering, and drug delivery.
A block copolymer having a plurality of target binding partners having affinity toward a target molecule covalently coupled thereto, the block copolymer having a first hydrophilic block and a second hydrophobic block, wherein the hydrophilic block comprises a plurality of carboxylic acid groups and a plurality of positive charged groups, and wherein the hydrophilic block is substantially electronically neutral.
A block copolymer comprising a first hydrophilic block and a second hydrophobic block, wherein the hydrophilic block comprises a plurality of carboxylic acid groups and a plurality of positive charged groups, and wherein the hydrophilic block is substantially electronically neutral.
Dependencies are inferred from the claim text.