Expression Process
AssigneeFujifilm Diosynth Biotechnologies UK Limited
InventorsBhupendra Vallabh Kara, Christopher David John Lennon
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Abstract
A process for the production of a target recombinant polypeptide is provided. The process comprises expressing an expression cassette encoding the target polypeptide and co-expressing an expression cassette encoding a mitochondrial foldase. Preferred mitochondrial foldases include Mia 40 and Erv1, and homologs thereof.
Claims22
A process of producing a target recombinant polypeptide which comprises expressing an expression cassette encoding the target polypeptide and a secretion leader and co-expressing an expression cassette encoding a mitochondrial foldase and a secretion leader.
(canceled)
A protein expression system comprising an expression cassette encoding a target polypeptide and a secretion leader and an expression cassette encoding a mitochondrial foldase and a secretion leader.
(canceled)
A vector comprising an expression cassette encoding a mitochondrial foldase secretion leader.
(canceled)
Dependencies are inferred from the claim text.