Method of inducing differentiation from pluripotent stem cells to skeletal muscle cells
AssigneeKyoto Universtiy
InventorsHidetoshi Sakurai, Akihito Tanaka, Knut Woltjen, Makoto Ikeya
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Abstract
The present invention provides a method of producing a skeletal muscle cell from a pluripotent stem cell, which includes a step of expressing one or more exogenous factors selected from MyoD, Myf5 and nucleic acids encoding them on a pluripotent stem cell.
Claims15
A method of producing a skeletal muscle cell from a pluripotent stem cell, comprising a step of expressing one or more exogenous factors selected from MyoD, Myf5 and nucleic acids encoding them in the pluripotent stem cell.
10-12. (canceled)
A kit for inducing a skeletal muscle cell from a pluripotent stem cell, comprising one or more factors selected from MyoD, Myf5 and nucleic acids encoding them.
A pluripotent stem cell having a drug responsive inducible vector containing a nucleic acid encoding MyoD or Myf5.
Dependencies are inferred from the claim text.