Non-immunogenic delivery vehicle for betta-, gamma-, and delta-tocopherols and methods of using and making same
AssigneePhosphorex, Inc.
InventorBin Wu
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Abstract
This disclosure provides microparticles for the delivery of non-immunogenic compositions providing delivery of β-, γ- and/or δ-tocopherols.
Claims27
A composition comprising a microemulsion comprising one or more polyglycol esters, one or more of β, γ or δ-tocopherol and water, wherein the microemulsion comprises droplets between 1 nm and 1000 nm in diameter.
A non-immunogenic composition comprising a microparticle between 20 nm and 500 nm in diameter comprising one or more of β, γ or δ-tocopherol and one or more polymers wherein the one or more polymers release the tocopherol upon administration to a subject.
A method of making a drug delivery vehicle comprising
- a) dissolving a polymer in an organic solvent to form a solution;
- b) mixing one or more of β, γ or δ-tocopherol with the solution to form an emulsion;
- and
- c) mixing the emulsion with aqueous solution comprising a surfactant to form microparticles,
- thereby making a drug delivery vehicle.
Dependencies are inferred from the claim text.