Estradiol formulations and therapies
AssigneeTherapeuticsMD, Inc.
InventorsBrian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
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Abstract
Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Claims18
A composition comprising solubilized estradiol and a solubilizer comprising a medium chain oil, wherein the estradiol is at least 80% solubilized in the solubilizer, wherein the medium chain oil comprises substantially C6-C12 fatty acid esters, and wherein the composition is for oral administration.
Dependencies are inferred from the claim text.