Adhering composition and methods of applying the same
AssigneeTechnion Research & Development Foundation Limited
InventorsHavazelet BIANCO-PELED, Ohad KIMHI
Life of this patent
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Abstract
A method of in-situ adhering comprising providing pre-gel that comprises a mixture of at least one phenol-based compound and at least one water miscible polymer selected from at least one of a naturally existing form of a carbohydrate, a synthetically prepared form of carbohydrate and a salt of an anionic polysaccharide; spreading a layer of the pre-gel onto a first surface; adding a solid support, comprising at least one cross linking agent capable of interacting with the water miscible polymer to the pre-gel; and allowing the pre-gel to cure and adhere onto the first surface.
Claims20
A method of in-situ adhering comprising:
- providing pre-gel that comprises a mixture of at least one phenol-based compound and at least one water miscible polymer selected from at least one of a naturally existing form of a carbohydrate, a synthetically prepared form of carbohydrate and a salt of an anionic polysaccharide;
- spreading a layer of said pre-gel onto a first surface;
- adding a solid support, comprising at least one cross linking agent capable of interacting with said at least one water miscible polymer, to said pre-gel;
- allowing said pre-gel to cure and adhere onto the first surface.
A method of in-situ adhering comprising:
- providing pre-gel that comprises at least one phenol-based compound, at least one water miscible polymer selected from at least one of a naturally existing form of a carbohydrate, a synthetically prepared form of carbohydrate and a salt of an anionic polysaccharide, and a cross linking agent comprising at least one water-insoluble salt of multivalent ions capable of interacting with said at least one water miscible polymer;
- spreading a layer of said pre-gel onto a first surface;
- adding a solid support to said pre-gel;
- adding to and blending with the pre-gel at least one trigger compound capable of triggering release of multivalent ions from the cross linking agent into the pre-gel, allowing the pre-gel to cure and adhere to the first surface.
A method of treating an subject comprising:
- spreading a pre-gel onto a tissue of the subject, the pre-gel comprising a mixture of at least one phenol-based compound and at least one water miscible polymer selected from at least one of a naturally existing form of a carbohydrate, a synthetically prepared form of carbohydrate and a salt of an anionic polysaccharide;
- adding a solid support, comprising at least one cross linking agent capable of interacting with said at least one water miscible polymer, to said pre-gel;
- allowing said pre-gel to cure and adhere onto the tissue.
Dependencies are inferred from the claim text.