Conjugates of gm-csf and il-7, compositions and methods related thereto
AssigneesEmory University, Children's Health-Care of Atlanta, Inc.
InventorsJacques Galipeau, Hsiang-Chuan Hsieh
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Abstract
In certain embodiments, this disclosure relates to conjugates comprising GM-CSF and IL-7 and uses related thereto, e.g., enhancing the adaptive immune system. Typically the GM-CSF and IL-7 are connected by a polymer linker, e.g., polypeptide. In certain embodiments, the disclosure relates to nucleic acids encoding these polypeptide conjugates, vectors comprising nucleic acid encoding polypeptide conjugates, and protein expression systems comprising these vectors such as infectious viral particles and host cells comprising such a nucleic acids.
Claims21
A conjugate comprising a GM-CSF polypeptide and an IL-7 polypeptide.
A nucleic acid encoding a GM-CSF/IL-7 conjugate.
21-23. (canceled)
Dependencies are inferred from the claim text.