Automatic synthesizer apparatus for producing radiopharmaceutical tumor imaging agent Gallium-68-DOTATATE and method thereof
AssigneeInstitute of Nuclear Energy Research
InventorMing-Hsin Li
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Abstract
The invention provides an automatic synthesizer apparatus and method for producing radiopharmaceutical tumor imaging agent Gallium-68-DOTATATE with one button control process to effectively isolate the medication in vials from the contamination of environment and manual operations, saving the costs of investment in production with alleviation of the critical standard required for the environmental equipments to be used for production.
Claims4
An automatic synthesizer apparatus for producing radiopharmaceutical tumor imaging agent Gallium-68-DOTATATE, comprising first reagent vial being connected to first micro pump, and connected to GA-68-DOTATATE reactor and a waste vial through first solenoid valve and connected to C-18 reversed phase chromatography through fifth micro pump, second reagent vial being connected to C-18 reversed phase chromatography through second micro pump and connected to C-18 reversed phase chromatography through fifth micro pump, third reagent vial being connected to third micro pump, and connected to GA-68-DOTATATE reactor and C-18 reversed phase chromatography through second solenoid valve, respectively, fourth reagent vial being connected to micro pump and connected to GA-68-DOTATATE reactor and C-18 reversed phase chromatography through four solenoid valve, respectively, wherein the C-18 reversed phase chromatography is further connected to fifth and seventh solenoid valve, respectively, through sixth solenoid valve, in which the fifth solenoid valve is connected to fourth solenoid valve and third collection vial, in which the four solenoid valve is connected to first and second collection vial, respectively, wherein the sixth solenoid valve is connected to fourth collection vial and eighth solenoid valve, in which the eighth solenoid valve is connected to fifth and a spare collection vial, respectively.
Dependencies are inferred from the claim text.