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US 2014/0369588 A1Published application
Darkfield imaging system and methods for automated screening of calls
AssigneeQuorum Technologies Inc.
InventorJohn D. ARBUCKLE
Life of this patent
Estimating the term…
Abstract
The disclosure is directed at a system and method for darkfield imaging system and method for automated cell screening of cells. The system and method acquires multi- or hyperspectral digital darkfield images of cells and then processes the images to obtain measurements which can then be supplied or displayed to a user to analyze.
Claims21
1-20. (canceled)
A system for screening at least one cell comprising:
- image acquiring apparatus configured to acquire one or more images of the at least one cell in color at one or more of wavelengths and wavelength bands, via one or more of transmitted illumination and reflected illumination, the one or more of the transmitted illumination and the reflected illumination comprising one or more of oblique illumination and darkfield illumination;
- and,
- a processor, in communication with the image acquiring apparatus, the processor configured to:
- process chrominance data in the one or more images using one or more color space models to segment and measure one or more of specific cells and cell groups within the one or more images of the at least one cell, the chrominance data comprising native color information of the at least one cell.
1 more element
A method for screening at least one cell comprising:
- acquiring one or more images of the at least one cell in color at one or more of specified wavelengths and wavelength bands, via one or more of transmitted illumination and reflected illumination, the one or more of the transmitted illumination and the reflected illumination comprising one or more of oblique illumination and darkfield illumination, using an image acquiring apparatus;
- and,
- processing, using a processor, chrominance data in the one or more images using one or more color space models to segment and measure one or more of specific cells and cell groups within the one or more images, the chrominance data comprising native color information of the at least one cell.
Dependencies are inferred from the claim text.