Systems and methods for determining biomechanical properties of the eye for applying treatment

A system that determines biomechanical properties of corneal tissue, comprising:

• a light source configured to provide an incident light;
• a confocal microscopy system configured to scan the incident light across a plurality of cross-sections of the corneal tissue, the incident light being reflected by the plurality of cross-sections of corneal tissue as scattered light;
• a filter or attenuating device configured to block or attenuate the Rayleigh peak frequency of the scattered light;
• a spectrometer configured to receive the scattered light and process frequency characteristics of the received scattered light to determine a Brillouin frequency shift in response to the Rayleigh peak frequency being blocked or attenuated by the filter or attenuating device;
• and
• a processor configured to generate a three-dimensional profile of the corneal tissue according to the determined Brillouin frequency shift, the three-dimensional profile providing an indicator of one or more biomechanical properties of the corneal tissue.

A method for measuring biomechanical properties of the eye to at least one of plan, implement, or assess treatments of the eye, the eye having an iris and a cornea, the method comprising:

• directing an incident light from a light source, via a confocal microscopy system, at plurality of sections of the cornea, the incident light being scattered by the plurality of sections of the corneal tissue;
• receiving the scattered light in a spectrometer;
• processing frequency characteristics of the received scattered light to measure a Brillouin frequency shift in the scattered light;
• determining biomechanical data based on the measured Brillouin frequency shift;
• measuring a corneal topography of the eye;
• determining corneal topography data indicative of the measured corneal topography;
• imaging, via an image capture device, the iris;
• determining iris image data indicative of the imaged iris;
• determining, based on a processor clock provided by one or more processors, time stamp data for each of the biomechanical data, the corneal topography data, and the iris image data;
• storing the biomechanical data with the associated time stamp data in one or more memory devices;
• storing the corneal topography data with the associated time stamp data in the one or more memory devices;
• storing the iris image data with the associated time stamp data in the one or more memory devices;
• for each of the biomechanical data, determining which of the iris image data has the same associated time stamp data;
• for each of the corneal topography data, determining which of the iris image data has the same associated time stamp data;
• and
• determining three-dimensional voxel data by correlating each of the biomechanical data with each of the corneal topography data determined to have the same associated iris image data, each of the three-dimensional voxel data including an indication of at least one of the biomechanical data, at least one of the corneal topography data, and at least one of the iris image data.